王义

男

1982-10

学位：博士

职称：副研究员

导师身份：博士生导师

所属团队：程正迪首席科学家团队

教育和工作经历：

2000.9-2004.6  武汉大学 学士

2004.9-2007.6  复旦大学 硕士

2010.9-2014.6  复旦大学 博士

2007.7-2010.3  复旦大学 助理工程师

2010.4-2017.1  复旦大学 工程师

2015.8-2016.8  美国劳伦斯伯克利国家实验室 访问学者

2017.2-至今    东华大学先进低维材料中心 青年研究员

研究方向：

[1] 基于多孔纳米材料的电化学催化及能源转化与储存。

[2] 基于低维度碳硅和半导体等纳米材料的生物传感、肿瘤诊断和治疗。

近几年承担的科研项目：

[1]国家自然科学基金子课题，2019-2021，靶向LRP1的碳纳米点跨越血脑屏障递送小分子或蛋白药物入脑

[2]国家自然科学基金，2017-2020，白介素-6受体介导的基于聚合物包裹碳纳米点的脑胶质瘤靶向识别与可视化联合治疗

[3]国家自然科学基金，2014-2016，超薄Y沸石纳米片及其复合物的合成、表征与催化性能

[4]上海市自然科学基金，2013-2016，实现肿瘤靶向联合诊疗的多功能磁性石墨烯-介孔硅纳米复合物的制备与表征

[5]技术开发项目，2019-2021，左炔诺孕酮长效制剂的开发

[6]技术开发项目，2011-2012，包裹Cyclopamine并嵌接A2B5抗体的介孔硅对脑胶质瘤化疗的研究

代表性论文：

进校之后：

1. Xu Y, Zhu L, Cui X, Zhao M, Li Y, Chen L, Jiang W, Jiang T, Yang S, Wang Y*. Graphitizing N-doped mesoporous carbon nanospheres via facile single atom iron growth for highly efficient oxygen reduction reaction. Nano Research 2020, 13(3):752-758.

2. Chen L, Xu J, Wang Y*, Huang RQ*. Ultra-small MoS₂ Nanodots-Incorporated Mesoporous Silica Nanospheres for pH-Sensitive Drug Delivery and CT Imaging. J. Mater. Sci. Technol. 2020, online.

3. Chen L#, Qian M#, Jiang H, Zhou Y, Du Y, Yang Y, Huo T, Huang R*, Wang Y*. Multifunctional mesoporous black phosphorus-based nanosheet for enhanced tumor-targeted combined therapy with biodegradation-mediated metastasis inhibition. Biomaterials 2020, 236: 119770.

4. Zhao M, Li Y, Lin F, Xu Y, Chen L, Jiang W, Jiang T, Yang S, Wang Y*. A Quasi-Solid-State Photothermal Supercapacitor via Enhanced Solar Energy Harvest. J. Mater. Chem. A 2020, 8(4): 1829-1836.

5. Qian M, Chen L, Du Y, Jiang H, Huo T, Yang Y, Guo W, Wang Y*, Huang R*. Biodegradable Mesoporous Silica Achieved via Carbon Nanodots-Incorporated Framework Swelling for Debris-Mediated Photothermal Synergistic Immunotherapy. Nano Lett. 2019, 19: 8409-8417.

6. Li Y, Zhao M, Xu Y, Chen L, Jiang T, Jiang W, Yang S*, Wang Y*. Manipulating light trapping and water vaporization enthalpy via porous hybrid nanohydrogels for enhanced solar-driven interfacial water evaporation with antibacterial ability. J. Mater. Chem. A 2019, 7: 26769-26775.

7. Cui X, Xu Y, Chen L, Zhao M, Yang S, Wang Y*. Ultrafine Pd nanoparticles supported on zeolite-templated mesocellular graphene network via framework aluminum mediation: An advanced oxygen reduction electrocatalyst. Applied Catalysis B: Environmental 2019, 244: 957-964.

8. Li Y, Cui X, Zhao M, Xu Y, Chen L, Cao Z, Yang S*, Wang Y*. Facile Preparation of Robust Porous Photothermal Membrane with Antibacterial Ability for Efficient Solar-driven Interfacial Water Evaporation. J. Mater. Chem. A 2018, In press.

9. Zhao M, Cui X, Xu Y, Chen L, He Z, Yang S, Wang Y*. An ordered mesoporous carbon nanosphere-encapsulated graphene network with optimized nitrogen doping for enhanced supercapacitor performance. Nanoscale 2018, 10(32): 15379-15386.

10. Cui X, Li Y, Zhao M, Xu Y, Chen L, Yang S, Wang Y*. Facile growth of ultra-small Pd nanoparticles on zeolite-templated mesocellular graphene foam for enhanced alcohol electrooxidation. Nano Research 2019, In press.

11. Qian W#, Qian M#, Wang Y#, Huang J, Chen J, Ni L, Huang Q, Liu Q, Gong P, Hou S, Zhu H, Jia Z, Shen D, Zhu C, Jiang R, Sun J, Yao J, Tang Z, Ji X, Shi J*, Huang R*, Shi W*. Combination Glioma Therapy Mediated by a Dual-Targeted Delivery System Constructed Using OMCN-PEG-Pep22/DOX. Small 2018, 14: 1801905. (cover page)

12. Li C, Wang Y*, Du Y, Qian M, Jiang H, Wang J, Murthy N, Huang R*. Side effects-avoided theranostics achieved by biodegradable magnetic silica-sealed mesoporous polymer-drug with ultralow leakage. Biomaterials 2018, 186: 1-7.

13. Qian M, Du Y, Wang S, Li C, Jiang H, Shi W, Chen J, Wang Y*, Wagner E, Huang R*. Highly Crystalline Multicolor Carbon Nanodots for Dual-Modal Imaging-Guided Photothermal Therapy of Glioma. ACS Appl. Mater. Interfaces 2018, 10: 4031-4040.

14. Cui X, Wang X, Xu X, Yang S, Wang Y*. One-step stabilizer-free synthesis of porous bimetallic PdCu nanofinger supported on graphene for highly efficient methanol electro-oxidation. Electrochimica Acta 2018, 260: 47-54.

15. Wang S, Li C, Qian M, Jiang H, Shi W, Chen J, Lachelt U, Wagner E, Lu W, Wang Y*, Huang R*. Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots. Biomaterials 2017, 141: 29-39.

16. Wang S, Li C, Meng Y, Qian M, Jiang H, Du Y, Huang R, Wang Y*. MemHsp70 Receptor-mediated Multifunctional Ordered Mesoporous Carbon Nanospheres for Photoacoustic Imaging-Guided Synergistic Targeting Trimodal Therapy. ACS Biomater. Sci. Eng. 2017, 3: 1702-1709.

17. Shi W, Cui X, Shi J, Chen J, Wang Y*. Overcoming the blood-brain barrier for glioma-targeted therapy based on an interleukin-6 receptor-mediated micelle system. RSC Adv. 2017, 7: 27162-27169.

进校之前：

1. Wang Y, Wang S, Li C, Qian M, Bu J, Wang J, Huang R. Facile Growth of Well-dispersed and Ultra-small MoS2 Nanodots in Ordered Mesoporous Silica Nanoparticles. Chem. Commun. 2016, 52:10217-10220. (cover page)

2. Wang Y, Shi W, Wang S, Li C, Qian M, Chen J, Huang R. Facile Incorporation of Dispersed Fluorescent Carbon Nanodots into Mesoporous Silica Nanosphere for pH-triggered Drug Delivery and Imaging. Carbon 2016, 108:146-153.

3. Meng Y, Wang S, Li C, Qian M, Yan X, Yao S, Peng X, Wang Y*, Huang R*. Photothermal combined gene therapy achieved by polyethyleneimine-grafted oxidized mesoporous carbon nanospheres. Biomaterials 2016, 100:134-142.

4. Ye D, Wang L, Zhang R, Liu B, Wang Y*, Kong J*. Facile preparation of N-doped mesocellular graphene foam from sludge flocs for highly efficient oxygen reduction reaction. J. Mater. Chem. A 2015, 3:15171-15176. 

5. Ye D, Zhang R, Fu Y, Bu J, Wang Y*, Liu B, Kong J*. Co-calcination-derived Pd budded in N-Doped Ordered Mesoporous Graphitic Carbon Nanospheres for Advanced Methanol-tolerant Oxygen Reduction. Electrochimica Acta 2015, 160:306-312.  

6. Wang Y, Meng Y, Wang S, Li C, Shi W, Chen J, Wang J, Huang R. Direct Solvent-Derived Polymer-Coated Nitrogen-Doped Carbon Nanodots with High Water Solubility for Targeted Fluorescence Imaging of Glioma. Small 2015, 11(29):3575-81. (cover page)(Highlighted by MaterialsViewsChina  http://www.materialsviewschina.com/2015/04/one-step-conversion-preparation-of-solvent-available-for-targeted-imaging-of-brain-glioma-in-water-soluble-polymer-coated-nitrogen-doped-carbon-nanotubes/  ) 

7. Wang K,Yao H,Meng Y,Wang Y*,Yan X*,Huang R*. Specific aptamer-conjugated mesoporous silica-carbon nanoparticles for HER2-targeted chemo-photothermal combined therapy.Acta Biomater. 2015, 16:196-205.

8. Wang Y, Wang K, Zhang R, Liu X, Yan X, Wang J, Wagner E, Huang R. Synthesis of Core-Shell Graphitic Carbon@Silica Nanospheres with Dual-Ordered Mesopores for Cancer-Targeted Photothermochemotherapy. ACS Nano 2014, 8(8):7870-7879.

9. Yao H, Wang K, Wang Y, Wang S, Li J, Lou J, Ye L, Yan X, Lu W, Huang R. Enhanced blood-brain barrier penetration and glioma therapy mediated by a new peptide modified gene delivery system. Biomaterials 2015, 37:345-352. (co-first author)

10. Wang Y, Huang R, Liang G, Zhang Z, Zhang P, Yu S, Kong J. MRI-Visualized, Dual-targeting and Combined Tumor Therapy Using Magnetic Graphene-based Mesoporous Silica. Small 2014, 10(1):109-116. (cover page)

11. Wang Y, Wang K, Yan X, Huang R. A General Strategy for Dual-triggered Combined Tumor Therapy based on Template Semi-graphitized Mesoporous Silica Nanoparticles. Adv. Healthc. Mater. 2014, 3(4):485-489. (Highlighted by MaterialsViewsChina，网址：http://www.materialsviewschina.com/2014/05/bian-fei-wei-bao-ce-l/  ) . 

12. Wang Y, Li H, Kong J. Facile Preparation of Mesocellular Graphene Foam for Direct Glucose Oxidase Electrochemistry and Sensitive Glucose Sensing. Sensor Actuat. B-Chem. 2014, 193:708-714. 

13. Wang Y, Wang K, Zhao J, Liu X, Bu J, Yan X, Huang R. Multifunctional Mesoporous Silica-coated Graphene Nanosheet used for Chemo-Photothermal Synergistic Targeted Therapy of Glioma.J. Am. Chem. Soc. 2013, 135(12):4799-4804.（ESI高被引论文）

14. Wang Y, Sun H, Zhang R, Yu SN, Kong J. Large Scale Templated Synthesis of Single-layered Graphene with A High Electrical Capacitance. Carbon 2013, 53:245-251.

15. Wang Y, Shi W, Song W, Wang L, Liu X, Chen J, Huang R. Tumor Cell Targeted Delivery by Specific Peptide-modified Mesoporous Silica Nanoparticles. J. Mater. Chem. 2012, 22(29):14608-14616.

16. Wang Y, Zhang S, Chen H, Li H, Zhang P, Zhang Z, Liang G, Kong J. One-pot Facile Decoration of Graphene Nanosheets with Ag Nanoparticles for Electrochemical Oxidation of Methanol in Alkaline Solution. Electrochem. Commun. 2012, 17:63-66.