Abstract：A silver‐mediated oxidative difluoromethylation of styrenes and vinyl trifluoroborates with TMSCF 2 H is reported for the first time. This method enables direct and facile access to CF 2 H‐alkenes from abundant alkenes with excellent functional group compatibility . Moreover, this Ag/TMSCF 2 H protocol could further enable a series of radical difluoromethylation of a wide array of substrates, offering a generic and complementary platform for the construction of diversified C‐CF 2 H bonds.

原文链接：https://onlinelibrary.wiley.com/doi/10.1002/anie.202014587